PT-141 (10mg)

Overview

PT-141 (Bremelanotide) is a synthetic peptide melanocortin receptor agonist developed specifically for sexual dysfunction research. Unlike other approaches that work peripherally, PT-141 acts through the central nervous system to enhance sexual desire and arousal. It's a metabolite of Melanotan II with more selective effects on sexual function.

Mechanism of Action

• •Activates melanocortin receptors (MC3R and MC4R) in the central nervous system
• •Stimulates sexual arousal through hypothalamic pathways
• •Enhances dopamine and other neurotransmitters involved in desire
• •Works centrally rather than through vascular mechanisms
• •Affects both psychological and physiological aspects of arousal
• •Independent of testosterone levels or vascular function

Research Applications

• •Sexual dysfunction research (male and female)
• •Hypoactive sexual desire disorder (HSDD) studies
• •Female sexual arousal disorder research
• •Erectile dysfunction investigations
• •Libido and desire research
• •CNS-mediated sexual function studies

Key Research Findings

• •FDA-approved for female sexual dysfunction (as Vyleesi)
• •Research shows significant improvements in sexual desire and arousal
• •Studies demonstrate effectiveness in both men and women
• •Works through unique CNS mechanism unlike PDE5 inhibitors
• •May be effective when other treatments fail

Dosage Guidelines

Research protocols typically use 0.5-2 mg administered subcutaneously, 30-60 minutes before desired effects. Effects last 4-6 hours. Not for daily use - research protocols use as-needed dosing. Reconstitute with bacteriostatic water. For research purposes only.

Storage Instructions

Store lyophilized powder at 2-8°C (refrigerated). Once reconstituted, store at 2-8°C and use within 30 days. Protect from light.